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pentobarbital will lessen the level or result of colchicine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.pentobarbital will decrease the extent or effect of bexarotene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.pentobarbital will lower the level or outcome of lumacaftor/ivacaftor b